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Compass Pathways Launches TRD Education Campaign at Psych Congress 2026

At a glance

  • Compass Pathways introduced “Change the Tune in TRD” at Psych Congress 2026.
  • The campaign focuses on treatment-resistant depression (TRD) education for U.S. healthcare providers.
  • New data on TRD patient outcomes and healthcare costs were presented at the event.

Compass Pathways plc announced the launch of a new educational initiative for healthcare providers, “Change the Tune in TRD,” during Psych Congress 2026 in New Orleans, which took place from September 14 to 19, 2026.

The campaign was introduced through a three-panel session on September 15, 2026, at the congress, aiming to address treatment-resistant depression (TRD) among U.S. healthcare professionals.

The program brings together specialists from psychotherapy, general psychiatry, and interventional psychiatry to discuss the neurobiology of TRD, care pathways, and methods for clinicians to recognize TRD in patients.

Compass Pathways stated that the campaign seeks to improve early and consistent identification of TRD by offering digital resources and perspectives from key opinion leaders in the field.

What the numbers show

  • TRD patients experience nearly three times longer depressive episodes than those with major depressive disorder (MDD.
  • Remission rates for TRD are 13%, compared to 42% for MDD patients.
  • Relapse rates are higher in TRD patients at 53%, versus 31% for MDD.

During Psych Congress 2026, Compass Pathways presented new health economics and outcomes research data, which included findings on real-world healthcare costs, resource utilization, and challenges in identifying TRD in clinical settings.

The company’s COMP360 psilocybin program for TRD has received Breakthrough Therapy designation from the U.S. Food and Drug Administration and Innovative Licensing and Access Pathway designation in the United Kingdom.

Compass Pathways is conducting what it states is the world’s largest classic psychedelic clinical program in TRD and is progressing with late-stage clinical trials of COMP360 for post-traumatic stress disorder (PTSD.

* This article is based on publicly available information at the time of writing.

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